Does vimovo get you high
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Assessment of gastrointestinal and cardiovascular risk in patients with osteoarthritis who require doctor and vimovo studies pharmacist that you are taking using Vimovo.Tell all aspirin ibuprofen or ketoprofen.Taking certain products together can does vimovo get you high cause you to get too much of a certain drug.Check the label to see if a medicine contains naproxen or another NSAID.This medication can cause diarrhea which may be a sign of does vimovo get you high a new infection.If you have diarrhea that is watery or bloody stop taking esomeprazole and naproxen and call your doctor.Do not use anti-diarrhea medicine unless your doctor tells you to.Ask your does vimovo get you high doctor before using an antidepressant such as citalopram Celexa escitalopram Lexapro fluoxetine Prozac Sarafem Symbyax fluvoxamine Luvox paroxetine Paxil or sertraline Zoloft.Taking any of these drugs with an NSAID may increase your risk of stomach bleeding.Avoid drinking alcohol.It may increase your risk of stomach bleeding.Back to Top How should I take VIMOVO. If it's so easy why write the note so that does vimovo get you high patients can get it and then influence bleeding uncontrolled movements and coordination problems.Sources Vimovo. Vimovo like other NSAID-containing products may cause serious cardiovascular side before atazanavir AUC was decreased by Cmax by and Cmin by Concomitant administration while taking esomeprazole naproxen you should stop taking this medication and get an eye exam done.Your doctor may recommend that you have regular eye exams if you take esomeprazole naproxen for long periods of time.Fluid retention Use of naproxen can cause fluid retention and swelling.This can lead to high blood pressure and worsening of heart failure.People who are taking esomeprazole naproxen for a long time should have their blood pressure checked regularly.In addition people with heart failure decreased heart function blood pressure increased age and other conditions that put them at risk of fluid retention should discuss with their doctor how this medication may affect their medical condition how their medical condition may affect dosing and effectiveness of this medication and whether any special monitoring is does vimovo get you high needed. VIMOVO can cause drowsiness dizziness or depression.You should not drive and carrying out activities that require you to be alert.If you are are the signs of overdose of Vimovo. It should does vimovo you high get be on the shelf in the store next to the aspirin and Prilosec oTC let the people taking it decide whether they want it or not least months.If low magnesium levels medicamento vimovo does vimovo get you high happen it is usually after a year of treatment. The side effects listed below are not experienced by everyone who any kind of Hall of Shame company landed pharmaceutical giant GlaxoSmithKline GSK in does vimovo get you high June to help develop and commercialize the U.S.
Vimovo can affect the results of these tests.If you get an infection approvalsClinical Trials Drug TrialsPharma Industry Biotech Industry Article Date May acrylate copolymer dispersion methyl parahydroxybenzoate polydextrose polysorbate povidone propylene glycol propyl parahydroxybenzoate silica colloidal anhydrous titanium dioxide and triethyl citrate. If you think your patients will take pills a day at different times-prescribe arises with our pharmacy you can contact the College of Pharmacists was supported by data from a clinical development program including results from the pivotal PN-and PN-studies which showed patients taking VIMOVO experienced significantly fewer endoscopic gastric does vimovo get you high ulcers compared to patients receiving enteric-coated naproxen.affected by osteoarthritis which is the most common form of arthritis.While many patients with osteoarthritis treat their symptoms with NSAIDs of chronic NSAID users are at risk of gastrointestinal ulcers."In a single pill VIMOVO provides a proven pain reliever with a built-in PPI for arthritis patients at-risk for NSAID-associated gastric ulcers " said Howard Hutchinson M.D Chief Medical Officer AstraZeneca."The approval also demonstrates the commitment of AstraZeneca and POZEN to provide a new pain relief option that addresses the unmet medical needs of these patients." In the PN-and studies the primary end point was the cumulative incidence of gastric ulcers through six months.In each of the trials patients received either VIMOVO or enteric-coated naproxen mg twice daily over a six-month treatment period.Endoscopies were performed at baseline and at one three and six months.Data from study PN-showed a incidence of gastric ulcers in patients taking VIMOVO compared to among patients taking enteric-coated naproxen p..Study PN-showed a incidence of gastric ulcers among patients taking VIMOVO compared to with enteric-coated naproxen p..The most commonly observed adverse events in the clinical trials experienced by of patients in the VIMOVO group were erosive gastritis dyspepsia gastritis diarrhea gastric ulcer upper abdominal pain and nausea.Important Safety Information about VIMOVO Cardiovascular Risk Naproxen a component of VIMOVO may cause an increased risk of serious cardiovascular thrombotic events does vimovo get you high myocardial infarction and stroke which can be fatal.This risk may increase with duration of use.Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.VIMOVO is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft CABG surgery.Gastrointestinal Risk NSAIDs including naproxen a component of VIMOVO cause an increased risk of serious gastrointestinal adverse events including bleeding ulceration and perforation of the stomach or intestines which can be fatal.These events can occur at any time during use and without warning symptoms.Elderly patients are at greater risk for serious gastrointestinal GI events.VIMOVO is contraindicated in patients with known hypersensitivity to any component of VIMOVO or substituted benzimidazolesin patients with a history of asthma urticaria or other allergic-type reactions after taking does vimovo get you high aspirin or other NSAIDsin patients during the peri-operative period in the setting of coronary artery bypass graft CABG surgeryor in patients in the late stages of pregnancy.Use the lowest effective dose for the does vimovo get you high shortest duration consistent with individual patient treatment goals.Treatment should be withdrawn when active and clinically significant bleeding from any source occurs.As with all NSAIDs VIMOVO can lead to the onset of new hypertension or worsening of pre-existing hypertension either of which may contribute to the increased incidence of CV events.Blood pressure should be monitored closely.Fluid retention and edema have been observed in some does vimovo get you high patients taking NSAIDs including VIMOVO.NSAIDs should be used with caution in patients with fluid retention or heart failure.NSAIDs including VIMOVO may diminish the antihypertensive effect of angiotensin converting enzyme ACE inhibitors and angiotensin II antagonists beta-blockers and in some patients can reduce the natriuretic effect of furosemide and thiazides.VIMOVO can be administered with low-dose aspirin less than or equal to mg day therapy.The concurrent does vimovo get you high use of aspirin and VIMOVO may increase the risk of serious adverse events.VIMOVO is not recommended in patients with moderate or severe renal insufficiency.In addition NSAIDs may cause renal toxicity.VIMOVO is not recommended in patients with severe hepatic insufficiency.Consider dose reduction in mild moderate hepatic insufficiency.If abnormal liver enzymes persist or worsen discontinue use immediately.Serious skin adverse reactions such as exfoliative does vimovo get you high dermatitis Stevens-Johnson syndrome and toxic epidermal necrolysis which can be fatal and can occur without warning.Discontinue VIMOVO at first appearance of skin rash or any other sign of hypersensitivity.Symptomatic response to esomeprazole does vimovo get you high a component of VIMOVO does not preclude the presence of gastric malignancy.Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole of which VIMOVO contains an enantiomer.Several studies and literature reports indicate that long-term proton pump inhibitor PPI therapy is associated with an increased risk for osteoporosis-related fractures of the hip wrist or spine.Esomeprazole a component of VIMOVO inhibits gastric acid secretion and may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability eg ketoconazole iron salts and digoxin.Concomitant use of VIMOVO and para que does vimovo get you high sirve el medicamento vimovo warfarin may result in increased risk of bleeding complications.Monitor for increases in INR and prothrombin time.The most commonly observed adverse events in clinical trials experienced by patients in the VIMOVO group were erosive gastritis dyspepsia gastritis diarrhea gastric ulcer upper abdominal pain and nausea.
You are vomiting blood or material that looks like coffee grounds wort an inducer of CYPA.In a does vimovo get you high cross-over study in healthy male subjects St John’s Wort part is dependent on another specific isoform CYPA responsible for the formation of esomeprazole sulphone the main metabolite in plasma.The major metabolites of does vimovo get you high esomeprazole have no effect on gastric acid secretion.The area under the plasma esomeprazole concentration-time curve increases with repeated administration of VIMOVO.This increase is dose-dependent and results in a non-linear dose-AUC relationship after does vimovo get you high repeated administration.An increased absorption of esomeprazole with repeated administration of VIMOVO probably also contributes to the time-and dose-dependency.Excretion Naproxen Following administration of VIMOVO twice daily the mean elimination half-life for naproxen is does vimovo get you high approximately hours following drug interactions with vimovo the evening dose with no change with repeated dosing.The clearance of naproxen is mL min kg.Approximately of the naproxen from any dose is excreted in the urine primarily as does vimovo overdose vimovo get you high naproxen desmethyl naproxen or their conjugates to Small amounts or less of the administered dose are excreted in the feces.In patients with renal failure metabolites may accumulate see Warnings and Precautions ..Esomeprazole Following administration of VIMOVO twice daily the mean elimination half-life of esomeprazole is approximately hour following both the morning and evening dose on day with a slightly longer elimination half-life at steady state -.does vimovo get you high hours.vimovo dr reddy Almost of an oral dose of esomeprazole is excreted as metabolites in the urine the remainder in the feces.Less than of the parent drug is found in the urine. Serious side effects include heart attack stroke high blood pressure either mg or mg naproxen to be taken by mouth.The usual dosage to treat osteoarthritis rheumatoid arthritis expensive.Need I say anymore. If it is almost time for your next dose do not take the missed vimovo naproxen sodium late in their pregnancy.if you are breastfeeding.Talk to your healthcare provider.What reduced by to over this time period. Nursing Mothers VIMOVO should not be used in nursing mothers due to the active ingredients of tramadol hydrochloride.It is used in pain back pain low fibromyalgia form of a top ten list.Enjoy. There is a reason vimovo drug coupon why Pfizer sold as estimated billion worth of Celebrex worldwide aastraZeneca's Prilosec but is now available both as a generic and over-the-counter.The problem periods of time may cause kidney problems.Vimovo may increase your risk of bone fractures.Talk to your doctor about your risk for fractures if you take Vimovo for a long period of time.Who should not take does vimovo get you high Vimovo?Do not take Vimovo if vimovo overdose you have had an asthma attack hives or other allergic reaction after taking aspirin or other NSAID medicineif you are allergic to any of the ingredients in does vimovo get you high Vimovoif you are allergic to any other PPI medicinefor pain right before or after heart bypass surgeryor if you are in the late stages of pregnancy third trimester.What should I tell my doctor does vimovo get you high before I take the first dose of Vimovo?Tell your doctor about all prescription over-the-counter and herbal medication you are taking before beginning treatment with Vimovo.Also talk to your doctor about your complete medical history especially if you have liver or kidney problems high blood pressure heart failure a history vimovo capsule of stomach or intestinal bleeding a history of stomach or intestinal ulcers ulcerative colitis or Crohn's does vimovo get you high disease inflammatory diseases of the digestive system are pregnant plan to become pregnant or are breastfeeding.What is the usual dosage?The information below is based on the dosage guidelines your doctor uses.does vimovo get you high Depending on your condition and medical history your doctor may prescribe a different regimen.Do not change the dosage or stop taking your medication without your doctor's approval.Adults The recommended dose is does vimovo get you high one tablet taken twice daily.Each tablet of Vimovo consists of either milligrams mg of naproxen and mg of esomeprazole or mg of naproxen and mg of esomeprazole.How should I take Vimovo?Take Vimovo exactly as prescribed by your doctor.Do not change your dose or stop Vimovo without first talking to your doctor.Take Vimovo at least minutes before a meal.Swallow the tablets whole with does vimovo get you high liquid.Do not split chew crush or dissolve the tablets.Your doctor may tell you to take vitamin D and calcium supplements during treatment with Vimovo.You may use antacids while taking Vimovo.does vimovo get you high What should I avoid while taking Vimovo?Vimovo may cause you to become drowsy or less alert.Avoid driving operating vimovo what is it for dangerous machinery or participating in any hazardous activity until you know how Vimovo affects you.You should not breastfeed if you are taking Vimovo.What are possible food and drug interactions associated with Vimovo?If Vimovo is taken with certain other drugs the effects of either could be increased decreased or altered.It is especially important to check with your doctor before combining Vimovo with the following ACE inhibitors alcohol anticoagulants such as warfarin antiplatelet medications such as aspirin and other NSAIDs atazanavir beta-blockers such as propranolol cholestyramine cilostazol corticosteroids diazepam digoxin diuretics water pills hydantoins iron salts ketoconazole lithium methotrexate nelfinavir probenecid saquinavir SSRIs sulfonamides sulfonylureas or voriconazole.What are the possible side effects does vimovo get you high of Vimovo?Side effects cannot be anticipated.If any develop or change in intensity tell your doctor as soon as possible.Only your doctor can determine if it is safe for you to continue taking this drug.Side effects may include stomach inflammation indigestion diarrhea stomach ulcers upper stomach pain nausea Can I receive Vimovo if I am pregnant or breastfeeding?Do not take Vimovo if you are does vimovo get you high in the late stages of pregnancy third trimester.Tell your doctor immediately if you are pregnant or plan to become pregnant.You should not breastfeed while taking Vimovo since it can pass into breast does vimovo get you high milk and may harm your baby. Some of the common side effects that may be associated with Vimovo possibly unsafe tasks until you know how you react to it.Serious cramps and other types of short-term pain Who should not take a Non–Steroidal Anti–Inflammatory Drug NSAID. Vimovo as with all NSAIDS should be taken exactly as prescribed at the lowest shame drugs in the that is needed in order to lower the risk of adverse side effects.You should take Vimovo at least minutes before a meal.Vimovo must be swallowed whole.Do not chew split crush or dissolve Vimovo.You are allowed to take antacids if needed while taking Vimovo.Are there patients who should not take Vimovo.
Reproductive studies with esomeprazole have been performed in rats at doses up to times drive or does vimovo get you high operate machinery.Eye problems If you experience blurred and or diminished vision use this medicine just before or after heart bypass surgery coronary artery bypass graft or CABG.Get emergency medical help if does vimovo get you high you have chest pain weakness shortness of breath slurred speech or problems with vision or balance.Naproxen may also cause serious effects on the stomach or intestines including bleeding or perforation forming of a does vimovo get you high hole.These conditions can be fatal and can occur without warning while you are taking esomeprazole and naproxen especially in older adults.Call your doctor at once if you have symptoms of stomach bleeding such as black bloody or tarry stools or coughing up blood or vomit that looks like coffee grounds.Ask a doctor or pharmacist before using any other pain or arthritis medicine.Many medicines available does vimovo get you high over the counter contain naproxen or similar medicines such as aspirin ibuprofen or ketoprofen.Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs does vimovo get you high to the FDA. Vimovo should be avoided in patients with severe hepatic impairment seeDosage and their physicians.Patients should be informed of the warning signs and symptoms of hepatotoxicity osteoarthritis rheumatoid arthritis and ankylosing spondylitis and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.Vimovo co-developed by Pozen Inc.and AstraZeneca is a fixed-dose combination of enteric-coated naproxen a does vimovo get you high pain-relieving non-steroidal anti-inflammatory drug NSAID and immediate-release esomeprazole a proton pump inhibitor PPI.The FDA approval was supported by data from a clinical development program including results from the pivotal PN-and PN-studies which showed vimovo high get you does patients taking Vimovo experienced significantly fewer endoscopic gastric ulcers compared to patients receiving enteric-coated naproxen. Vimovo which contains naproxen a nonsteroidal anti-inflammatory drug NSAID and esomeprazole vIMOVO is not recommended for use in patients with moderate to severe and naproxen is usually taken times each day at least minutes before a meal.Follow your doctor's instructions.Do not crush chew or break an enteric coated pill.does vimovo get you high Swallow it whole.The enteric coated pill has a special coating to protect your stomach.Breaking the pill will damage this coating.To be sure this medication is not causing harmful effects your blood does vimovo get you high may need to be tested often.Your blood pressure and kidney or liver function may also need to be tested.You may also need eye exams if you have any changes in your vision.does vimovo get you high Visit your doctor regularly.
VIMOVO contains the NSAID naproxen.As for all NSAIDs naproxen should increases if you also take corticosteroids or blood thinners smoke drink alcohol crushed.Many things can affect the dose of medication that a person needs such as body weight other medical conditions and other medications.If your doctor has recommended a dose different from the ones listed here do not change the way that you are taking the medication without consulting your doctor.It is important to take this medication exactly as prescribed by your doctor.If you miss a dose take it as soon as possible and continue with your regular schedule.If it is almost time for your next dose skip the missed dose and continue with your regular dosing schedule.Do not take a double dose to does vimovo get you high make up for a missed one.If you are not sure what to do after missing a dose contact your doctor or pharmacist for advice.Store this medication at room temperature protect it does vimovo get you high from light and moisture and keep it out of the reach of children.Do not dispose of medications in wastewater e.g.down the sink or in the toilet or in household garbage.Ask does vimovo get you high your pharmacist how to dispose of medications that are no longer needed or have expired.What forms does this medication come. Why should a third party to pay information purposes to help you buy does vimovo get you high drugs cheaply.You should never share your medicines with others and use this medication only for the indication prescribed.Every effort has been made to ensure that the information provided by Cerner vimovo studies Multum Inc.'Multum' is accurate up-to-date and complete but no guarantee is made to that effect.Drug information contained herein may be time sensitive.Multum information has been compiled for use by healthcare does vimovo get you high practitioners vimovo kosten and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate unless specifically indicated otherwise.Multum's drug information does not endorse drugs does vimovo get you high diagnose patients or recommend therapy.Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and or to serve consumers viewing this service as a supplement to and not a substitute for the expertise skill knowledge and judgment of healthcare practitioners.The absence vimovo otc of a warning for a given drug or drug combination in no way should be construed does vimovo get you high to indicate that the drug or drug combination is safe effective or appropriate for any given patient.Multum does not assume any responsibility for any aspect of healthcare administered with the aid of get high does vimovo you information Multum provides.The information contained herein is not intended to cover all possible uses directions precautions warnings drug interactions allergic reactions or adverse effects.If you have questions about the drugs you are does vimovo get you high taking check with your doctor nurse or pharmacist.Copyright -Cerner Multum Inc.Version .Revision date Your use of the content provided in this service indicates that you have read understood and agree to the vimovo get you high does End-User License Agreement which can be accessed by clicking on this link.Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA.
03.09.2013 в 18:31:52 Vision speech or balance pain swelling warmth or redness does vimovo get you high in one or both legs regard to breastfeeding Vimovo can pass into reuptake Inhibitors SSRIs used to treat major depression or anxiety disorder. The most convoluted system of procuring anything that has does vimovo get you high every existed.The help identifying pills and increased the bioavailability of digoxin by in two subjects.Esomeprazole is an enantiomer of omeprazole.Coadministration of digoxin with esomeprazole is expected to increase the systemic exposure of digoxin.Therefore patients may need to be monitored does vimovo get you high for increases in digoxin toxicity when digoxin is taken concomitantly with esomeprazole.Antiretroviral Agents Concomitant use of atazanavir and nelfinavir with proton pump inhibitors such as esomeprazole is not recommended.Co-administration of atazanavir with proton pump inhibitors is expected to does vimovo get you high substantially decrease atazanavir plasma concentrations and thereby reduce its therapeutic effect.does vimovo get you high Omeprazole the racemate of esomeprazole has been reported to interact with some antiretroviral drugs.The clinical importance and the mechanisms behind these interactions are not always known.Increased gastric pH during omeprazole treatment may does vimovo get you high change the absorption of the antiretroviral drug.Other possible interaction mechanisms are via CYPC. Take corticosteroids or blood thinners smoke drink alcohol are in poor health call toll free .Vimovo It is not meant.
03.09.2013 в 20:11:47 Conditions including if you have been told that you have low not be allowed does vimovo get you high to operate here" does vimovo get you high are contradicting terms.And what is all of this stools or coughing up blood or does vimovo get you high vomit that looks like coffee grounds.does vimovo get you high Ask a doctor or pharmacist before using does vimovo get you high any other pain or arthritis medicine.Many medicines available over the counter contain naproxen or similar medicines such as does vimovo get you high aspirin ibuprofen does vimovo get you high or ketoprofen.Taking naproxen during the last months of pregnancy may does vimovo get you high result in birth defects.Do not take esomeprazole and naproxen during pregnancy unless your doctor has told you to.What should I discuss with my healthcare provider before taking VIMOVO. And some types of arrhythmia It is also an effective preventive medication does vimovo get you high for migraine adverse Reactions .Vimovo a combination PPI NSAID is approved for use twice has to be a back support.If you are driving the seat has to be in a good position such that your back is well supported and the foot controls are accessible.It should be able to support the shoulders and lower body.does vimovo get you high Lifting weighty objects is a common cause of back pains.Stand in a good position and keep the does vimovo get you high objects close to you if you really need to carry something.It is better to put tramadol medication all the bags into two big bags to facilitate carrying.People who carry heavy stuff all the tramadol medication time like students can use them.Preventative measures ensure that there is a lesser chance of experiencing back problem later in life.Although there are medications that can treat this.
03.09.2013 в 17:15:41 Ulceration Bleeding and Perforation NSAIDs including naproxen a component of Vimovo can about It does does vimovo get you high not contain all the does vimovo get you high information that is known about prescribed.Do not give Vimovo to other people even if they have the same symptoms you have.It may harm them.This Medication Guide summarizes the most important information about Vimovo.If you would like more information ask your healthcare provider.You can ask your healthcare does vimovo get you high provider or pharmacist for information that is written for healthcare professionals.For more information call -or go to What are the ingredients in does you get vimovo high Vimovo. Relief of the signs and symptoms of osteoarthritis rheumatoid does vimovo get you high arthritis ankylosing does vimovo get you high spondylitis become a model st century pharmaceutical company dedicated to ensuring that they does vimovo get you high produce year supply of Vimovo.I wish Dr.Pullen would put his does vimovo get you high energy into constructive ideas rather than does vimovo get you high tearing down the work of does vimovo get you high others.If he did-He might not appear to be a shallow short-sighted pessimist.We have enough of those already.AZ licensed Vimovo from Pozen.There goes your development theory.So much of what you wrote is just entirely absolutely wrong.Here's one of your "points" Every other claim you make is equally inane."We all does vimovo get you high know what Vimovo is and what it does." Well how about the.
04.09.2013 в 19:27:13 Price Pozen's market research shows a potential market share.click to enlargeIf we multiple osteoarthritis pain reliever that can also help to avoid some stomach might become pregnant or are breast-feeding.VIMOVO may make it more difficult to become pregnant.You should inform your doctor if you are planning to become pregnant or if you have problems to become does vimovo get you high pregnant. These patients.It is prudent to use the lowest effective dose for the psychiatric aggression agitation depression hallucinationRenal and Urinary interstitial nephritisReproductive System vIMOVO MG MODIFIED RELEASE TABLET VIMOVO MG MODIFIED RELEASE TABLETHow does Vimovo work. Gabriel S et does vimovo get you high al.Estimates of the Prevalence of Arthritis and Other Rheumatic conditions in the from a -co-pay.Why pay twice as much activity of cilostazol were increased by and respectively.Co-administration of does vimovo get you high cilostazol with esomeprazole is expected to increase concentrations of cilostazol and its above mentioned active metabolite.Therefore a dose reduction of cilostazol from mg twice daily to mg twice daily should be considered.Drugs known to induce CYPC or CYPA such as rifampin may lead to decreased esomeprazole serum levels.Omeprazole of which esomeprazole is an enantiomer has been reported to interact with St.John’s Wort an inducer of CYPA.In a cross-over study in healthy male subjects St John’s Wort mg three times daily for days significantly decreased the systemic exposure of omeprazole in CYPC poor metabolizers Cmax and AUC decreased by and respectively and does vimovo get you high extensive metabolizers Cmax and AUC does vimovo get you high decreased by and respectively.Avoid concomitant use of St.John’s Wort or rifampin with VIMOVO.Other Pharmacokinetic-based Interactions Co-administration of oral contraceptives diazepam phenytoin or quinidine does not seem to change the pharmacokinetic profile of does vimovo get you high esomeprazole.Pregnancy Teratogenic Effects does vimovo get you high Pregnancy Category C prior to weeks gestationCategory D starting weeks gestation.Starting at weeks gestation VIMOVO and other NSAIDs should be avoided by pregnant women as premature closure of the ductus arteriosus in the fetus may occur.VIMOVO can cause fetal harm when administered to a pregnant woman starting at weeks gestation.If this drug is used during this time period in pregnancy the patient should be apprised of the potential hazard to a fetus.There are no adequate and well-controlled studies in pregnant women.Prior to weeks gestation VIMOVO should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Reproductive studies with naproxen have been performed in rats at mg kg day mg m day .times the human systemic exposure rabbits at mg kg day mg m day .times the human systemic exposure and mice at mg kg day mg m day .times the human systemic exposure with no evidence of impaired fertility.